The blood-brain barrier is not a single barrier, but a composite of many systems that act to
control the entry of substances from the blood to the brain:
1. Capillary endothelial cells linked by tight junctions and expressing specialized uptake
systems for particular metabolic substrates (e.g., glucose, amino acids)
2. A prominent basement membrane between endothelia and adjacent cells
3. Pericapillary astrocytes with end-feet adjacent to capillaries
A similar system exists for the choroidal epithelium (blood-cerebrospinal fluid [CSF]
barrier).
Blood-brain Barrier Components?
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Seem to be useful to my experiment on 6-azido-hexanoic acid, I mean the skill.
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